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A01=Board on Life Sciences
A01=Committee on A Framework for Developing a New Taxonomy of Disease
A01=Division on Earth and Life Studies
A01=National Research Council
Age Group_Uncategorized
Age Group_Uncategorized
Author_Board on Life Sciences
Author_Committee on A Framework for Developing a New Taxonomy of Disease
Author_Division on Earth and Life Studies
Author_National Research Council
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Category1=Non-Fiction
Category=MJC
Category=MQW
COP=United States
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Language_English
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Price_€20 to €50
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Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease

Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for a new taxonomy of human disease based on molecular biology and develops a potential framework for creating one.

The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The new taxonomy that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia.

Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Table of Contents
  • Front Matter
  • Summary
  • 1 Introduction
  • 2 Why Now?
  • 3 What Would a Knowledge Network and New Taxonomy Look Like?
  • 4 How Do We Get There?
  • 5 Epilogue
  • References
  • Appendix A: The Statement of Task with Additional Context
  • Appendix B: Committee Biographies
  • Appendix C: March 1& 2, 2011 - Workshop Agenda
  • Appendix D: eMERGE Consortium Data Use Agreement
  • Appendix E: Glossary
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A01=Board on Life SciencesA01=Committee on A Framework for Developing a New Taxonomy of DiseaseA01=Division on Earth and Life StudiesA01=National Research CouncilAge Group_UncategorizedAuthor_Board on Life SciencesAuthor_Committee on A Framework for Developing a New Taxonomy of DiseaseAuthor_Division on Earth and Life StudiesAuthor_National Research Councilautomatic-updateCategory1=Non-FictionCategory=MJCCategory=MQWCOP=United StatesDelivery_Delivery within 10-20 working daysLanguage_EnglishPA=AvailablePrice_€20 to €50PS=Activesoftlaunch
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Product Details
  • Dimensions: 152 x 229mm
  • Publication Date: 16 Jan 2012
  • Publisher: National Academies Press
  • Publication City/Country: United States
  • Language: English
  • ISBN13: 9780309222228
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