Epilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.
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Product Details
Weight: 770g
Dimensions: 194 x 254mm
Publication Date: 10 Jan 2019
Publisher: Cambridge University Press
Publication City/Country: United Kingdom
Language: English
ISBN13: 9781107108356
About
Andrea Bernasconi M.D. is Professor of Neurology and epileptologist and Professor in the Integrated Program in Neuroscience at McGill University. He is founding Director of the Neuroimaging of Epilepsy Laboratory one of the core labs of the McConnell Brain Imaging Centre at the Montreal Neurologiocal Institute Montreal Canada. His research focuses on neuroimaging of malformations of cortical development particularly the design of computerized MRI analysis methods to automatically model pathological brain morphology. Neda Bernasconi M.D. is Professor in the Integrated Program in Neuroscience at McGill University and co-Director of the Neuroimaging of Epilepsy Laboratory at the McConnell Brain Imaging Centre of the Neurological Institute McGill University Montreal Canada. She is a world-renowned expert in advanced imaging of seizure disorders particularly those related to the limbic system. The goal of her research is to develop cutting-edge neuroimaging methods and combine them with statistical learning in search for epilepsy biomarkers. Matthias Koepp M.D. is Professor of Neurology at the University College London Institute of Neurology and Consultant Neurologist at the National Hospital for Neurology and Neurosurgery Queen Square London. He takes a particular interest in generalized epilepsies epilepsy and co-morbidities (depression). His research is focused on mechanisms of initiation and termination of epileptic seizures using molecular and functional imaging methods. In particular his work aims to clarify experimentally and clinically the mechanisms causes and associations of cerebral damage consequent upon epileptic seizures and epilepsy.