Palliative Care Formulary

The eighth edition of the Palliative Care Formulary (PCF8), from Pharmaceutical Press, the Royal Pharmaceutical Societys knowledge business, is an essential resource for health professionals who care for patients with progressive end-stage disease.

Although written primarily with cancer patients in mind, PCF8 contains specific material relating to several other life-limiting diseases e.g. COPD, end-stage heart failure, renal and hepatic failure, and end-stage Parkinson's disease.

Grounded in clinical practice, this comprehensive title includes independent information about drugs used in palliative care, highlighting off-label indications or routes, and dealing with the administration of multiple drugs by continuous subcutaneous infusion.

Updates in the new edition:

Renamed monograph (Tricyclic antidepressants) and two discontinued - (Carbamazepine and Danazol).

Fully reviewed and updated monographs with the latest references and evidence for all uses in palliative care including for:

All the individual strong opioid analgesic drug monographs and Quick Clinical Guides

Antidepressants class and individual drug monographs

Anti-epileptics class and individual drug monographs including a significantly updated section on the management of seizures and the use of subcutaneous levetiracetam

Bisphosphonates monograph including the 2020 ESMO clinical practice guidelines and a new joint summary table for the indications of use for bisphosphonates and denosumab in palliative care

Denosumab monograph including the 2020 ESMO clinical practice guidelines

Drugs and fitness to drive chapter including updates to the summary table of the available evidence for sedative drugs

Renal impairment chapter including significant changes to the sections on assessing renal function, and opioid use in renal impairment

Drug administration to patients with swallowing difficulties or enteral feeding tubes chapter including a new step-wise approach for alternative formulations, and a fully updated table on commonly used alternative products

Targeted updates to monographs including:

H2-receptor antagonists monograph updated to reflect the alternative oral and parenteral options due to the world-wide absence of ranitidine

Proton pump inhibitors monograph significant updates to the parenteral administration section

Clonidine monograph, involving significant updates to the dose and use section and a new summary of dexmedetomidine use

Drugs for diabetes monograph updated to include the 2021 Diabetes UK guidelines and the 2021 Joint British Diabetes Societies Inpatient Care Group guidelines. Significant changes to the sections on corticosteroid-induced diabetes mellitus, the management of hypoglycaemia, and the management of spikes of hyperglycaemia in the last few weeks of life

Systemic corticosteroids significant updates on the risks of adrenal insufficiency including information about the new steroid emergency card and information on the evidence of use for appetite stimulation

Anaphylaxis appendix updated to reflect the 2021 Resuscitation Council UK guidelines.

PCF8 also includes several Quick Clinical Guides covering key topics in palliative care and designed for everyday use.