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B01=Mukesh Nandave
B01=Priti Jain
Category1=Non-Fiction
Category=MF
Category=MJCL
Category=MMG
Category=MQP
Category=PN
Category=TCB
COP=Singapore
Delivery_Pre-order
Language_English
PA=Not yet available
Price_€100 and above
PS=Forthcoming
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PROTAC-Mediated Protein Degradation: A Paradigm Shift in Cancer Therapeutics

English

This book is a comprehensive coverage of the ubiquitin-proteasome system and its involvement in cancer progression, and the application of PROTACs in different types of cancer treatment. The book discusses a unique perspective and comprehensive knowledge of the potential of PROTACs to transform cancer therapies. It provides an overview of the history, mechanisms, chemistry, design considerations, and different technologies involved in PROTACs. Additionally, it explains the ubiquitin-proteasome system, its impact on various diseases, and the principles and mechanisms of UPS. The book also describes the chemistry and design aspects of PROTACs and their role in various types of cancers. Finally, it covers the pharmaceutics aspect of formulation design, global requirements, and toxicological aspects of PROTACs. This book is targeted at cancer researchers, medical oncologists, bioinformatics, computational biologists, pharmacologists, medicinal chemists, formulation scientists, regulatory authorities, and policy makers.

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Current price €183.34
Original price €192.99
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Age Group_Uncategorizedautomatic-updateB01=Mukesh NandaveB01=Priti JainCategory1=Non-FictionCategory=MFCategory=MJCLCategory=MMGCategory=MQPCategory=PNCategory=TCBCOP=SingaporeDelivery_Pre-orderLanguage_EnglishPA=Not yet availablePrice_€100 and abovePS=Forthcomingsoftlaunch

Will deliver when available. Publication date 07 Oct 2024

Product Details
  • Dimensions: 155 x 235mm
  • Publication Date: 07 Oct 2024
  • Publisher: Springer Verlag Singapore
  • Publication City/Country: Singapore
  • Language: English
  • ISBN13: 9789819750764

About

Dr. Mukesh Nandave is currently serving as the Associate Dean (Research & Consultancy) and Associate Professor as well as the Head of the Department of Pharmacology and Pharmaceutical Biotechnology at Delhi Pharmaceutical Sciences and Research University under the Government of NCT of Delhi India. Dr. Nandave completed his Ph.D. in Pharmacology from AIIMS in Delhi and pursued his post-doctoral training at the Ohio State University Medical Center in Columbus USA. Dr. Nandave has primarily focused his research on investigating the role of nutraceuticals herbomineral formulations and phytoconstituents in areas such as myocardial ischemia & reperfusion injury diabetes obesity cancer and pain management. He has published over 120 papers in national and international peer-reviewed journals and received several prestigious awards including the distinguished leadership award of the International Academy of Cardiovascular Sciences and holds various professional memberships.   Dr. Priti Jain is an Assistant Professor at the Department of Pharmaceutical Chemistry Delhi Pharmaceutical Sciences and Research University New Delhi. She has more than 15 years of experience in industrial and academic research. Her area of research is mainly focused on in silico design and the discovery of low molecular weight heterocycles as anti-Alzheimers agents anti-cancer agents and anti-HIV agents. Dr Jain is involved in research on analytical method development and validation of API and dosage forms. She has published more than 40 research articles in peer-reviewed international journals and authored or co-authored numerous books and book chapters. Jain serves as an editor for various journals and a reviewer of many reputed journals. She is also a Bentham Brand Ambassador since 2018 and has been conferred with various awards. She is a member of many international scientific societies and organizations.

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